Anion Gap Blood

Cancers such as multiple myeloma or those causing low albumin levels may be associated with a low anion gap. Low albumin, an essential protein, often results from cancer-related malnutrition or liver involvement.

Conditions like diabetic ketoacidosis, chronic kidney disease, and lactic acidosis commonly cause a high anion gap. Poisonings (e.g., antifreeze, salicylates) and severe dehydration are also significant contributors.

No, dehydration typically leads to a high anion gap, as it causes metabolic acidosis by concentrating acids in the blood. A low anion gap is more often linked to low albumin or laboratory errors.